Openness has been a feature of higher education for many decades, particularly through the establishment of open universities, although there remain debates about what openness means in practice.Digital technologies, some based on open principles, and digital content, aided by open licences, have both contributed recently to an extension of what is
Background: Triple-negative breast cancer (TNBC) remains difficult to be targeted.SET and cancerous inhibitor of protein phosphatase 2A (CIP2A) are intrinsic protein-interacting inhibitors of protein phosphatase 2A (PP2A) and frequently overexpressed in cancers, whereas reactivating PP2A activity has been postulated as an anti-cancer strategy.Here
Mutations in coding and non-coding regions of FUS cause amyotrophic lateral sclerosis (ALS).The latter mutations may exert toxicity by increasing FUS accumulation.We show here that broad expression within the nervous system of wild-type or either of two 99% ALOE VERA ALS-linked mutants of human FUS in mice produces progressive motor phenotypes acco
Background.Exoenzyme-producing gut microbiota and their likely use as probionts have been widely investigated in major carps.However, reports on exoenzyme-producing capacity together with inhibition of fish pathogens are scarce.The presently reported study aimed at characterization of novel probionts from the gastro-intestinal (GI) tract of an Indi